Beyond coincidence:
when schizophrenia coexists
with substance use disorders
This chapter explores the connection between schizophrenia and substance use
disorders (SUD), and the key factors behind their overlap. While challenges exist,
understanding their complex relationship opens the door to better support and
improved outcomes for individuals and their families.
Fast Facts
High prevalence of comorbidity: Nearly 50% of individuals with schizophrenia also experience substance use disorders, significantly
complicating recovery and emphasizing the need for integrated treatment.
Complex connection: The co-occurrence of schizophrenia and substance use disorders results from a complex interaction of brain dysfunctions, biological risks, self-medication, and social and environmental factors.
Protective strategies can promote recovery: Adherence to treatment, strong support networks, and integrated care are essential in managing these coexisting disorders and improving outcomes for individuals and their families.